Large, advanced tumours can press on other organs such as the bladder, causing incontinence (reduced bladder control) or making urination difficult or painful. Problems related to urination may occur as a result of prostate cancer because the urethra (the tube that carries urine from the bladder out of the body) passes directly through the prostate gland. These tumours may also interfere with the nerves responsible for erection of the penis, which leads to erectile dysfunction.
Advanced tumours can also cause:
- pain by pressing on the spine or pelvis
- burning or pain when urinating
- frequent urination
- pain when ejaculating
- blood to appear in the urine or semen
- pain or stiffness in the lower back, hips, or upper thighs
As well as travelling by blood, loose cancerous cells can be carried through the lymphatic system, which is a network of tubes that carry lymph (a clear liquid containing waste products and immune cells). From there, it can spread to various lymph nodes and other organs. The lymphatic system is the main carrier of metastases in prostate cancer. Secondary tumours can grow almost anywhere in the body, such as the lungs, brain, lymph nodes, however, it is most likely to spread to the bone
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